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A 52-year-old male presented to his primary care physician in February 2006, complaining of decreasing exercise endurance. The patient was a runner, and typically ran 5-8 miles three or four times a week. During the past month, he noted difficulty in completing the longer runs, and initially attributed this to a persistent cold and URI.
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Even in people who had never smoked cigarettes, pipe and cigar smoking was associated with decreased lung function and increased odds of airflow obstruction.
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Staging of chronic kidney disease (CKD) is based primarily upon estimated GFR. Proteinuria (PRO) is a strong marker for kidney disease, yet its severity is not included in current risk stratification schemes, which are instead driven by GFR.
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For women with suspected urinary tract infection, there is no advantage to routinely sending midstream urine samples for testing; antibiotics based on dipstick tests with a delayed prescription as backup, or empirical delayed prescription, can help to reduce antibiotic use.
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Nonspecific chest pain is a persistent illness and patients with it are subject to overly extensive work-ups.
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The FDA has approved a potassium channel blocker to improve walking in adults with multiple sclerosis.
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Even if asymptomatic, early elective aortic valve replacement should be considered for increasingly symptomatic patients with severe aortic valve stenosis because they have a poor prognosis with a high event rate and a risk of rapid functional deterioration, especially if the peak aortic jet velocity is above 5.5 m/sec.
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The burgeoning population of individuals with type 2 diabetes corresponds to a parallel increase in obesity.